A novel use of arterial spin labelling MRI to demonstrate focal hypoperfusion in individuals with posterior cortical atrophy: a multimodal imaging study.

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作者： Manja,Lehmann ^[1] ; Andrew,Melbourne ^[2] ; John C,Dickson ^[3] ; Rebekah M,Ahmed ^[1] ; Marc,Modat ^[2] ; M Jorge,Cardoso ^[2] ; David L,Thomas ^[4] ; Enrico,De Vita ^[5] ; Sebastian J,Crutch ^[1] ; Jason D,Warren ^[1] ; Colin J,Mahoney ^[1] ; Jamshed,Bomanji ^[3] ; Brian F,Hutton ^[3] ; Nick C,Fox ^[1] ; Xavier,Golay ^[6] ; Sebastien,Ourselin ^[2] ; Jonathan M,Schott ^[1]

作者单位： Dementia Research Centre, UCL Institute of Neurology, London, UK. ^[1] Translational Imaging Group, Centre for Medical Image Computing, University College London, London, UK. ^[2] Institute of Nuclear Medicine, University College London Hospitals, London, UK. ^[3] Dementia Research Centre, UCL Institute of Neurology, London, UK Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, UK. ^[4] Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, UK Neuroradiological Academic Unit, Brain Repair & Rehabilitation, UCL Institute of Neurology, London, UK. ^[5] Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, UK. ^[6]

关键词 ALZHEIMER'S DISEASE AMYLOID CEREBRAL BLOOD FLOW MRI PET, LIGAND STUDIES