Heterogeneous alleles comprising G6PD deficiency trait in West Africa exert contrasting effects on two major clinical presentations of severe malaria.

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作者： Shivang S,Shah ^[1] ; Kirk A,Rockett ^[2] ; Muminatou,Jallow ^[3] ; Fatou,Sisay-Joof ^[4] ; Kalifa A,Bojang ^[4] ; Margaret,Pinder ^[5] ; Anna,Jeffreys ^[4] ; Rachel,Craik ^[6] ; Christina,Hubbart ^[7] ; Thomas E,Wellems ^[8] ; Dominic P,Kwiatkowski ^[9] ; MalariaGEN Consortium ^[10]

作者单位： Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. ssshah03@gmail.com. ^[1] Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. ssshah03@gmail.com. ^[2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. krockett@well.ox.ac.uk. ^[3] Medical Research Council Laboratories, Banjul, Fajara, The Gambia. info@cggh.org. ^[4] Medical Research Council Laboratories, Banjul, Fajara, The Gambia. kbojang@mrc.gm. ^[5] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. anna.richardson@well.ox.ac.uk. ^[6] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. rachel.craik@obs-gyn.ox.ac.uk. ^[7] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. christina.hubbart@well.ox.ac.uk. ^[8] Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. TWELLEMS@niaid.nih.gov. ^[9] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. dominic@well.ox.ac.uk. ^[10] Wellcome Trust Sanger Institute, Hinxton, UK. dominic@well.ox.ac.uk. ^[11]

主题词成年人(Adult);非洲, 西部(Africa, Western);等位基因(Alleles);病例对照研究(Case-Control Studies);女(雌)性(Female);遗传关联研究(Genetic Association Studies);葡糖磷酸脱氢酶(Glucosephosphate Dehydrogenase);人类(Humans);疟疾(Malaria);男(雄)性(Male);中年人(Middle Aged);多态现象, 遗传(Polymorphism, Genetic)

DOI 10.1186/s12936-015-1045-0

PMID 26738565

发布时间 2022-01-29

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Malaria journal

2016年15卷

13页

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Heterogeneous alleles comprising G6PD deficiency trait in West Africa exert contrasting effects on two major clinical presentations of severe malaria.

Malaria journal

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Malaria journal

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Heterogeneous alleles comprising G6PD deficiency trait in West Africa exert contrasting effects on two major clinical presentations of severe malaria.

Malaria journal

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Malaria journal

相关期刊

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