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Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes.

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第一作者: Hernan,Lorenzi
第一单位: Department of Infectious Diseases, The J. Craig Venter Institute, 9704 Medical Center Drive, Rockville, Maryland 20850, USA.
作者单位: Department of Infectious Diseases, The J. Craig Venter Institute, 9704 Medical Center Drive, Rockville, Maryland 20850, USA. [1] Department of Molecular Microbiology, Washington University School of Medicine, 660 S. Euclid Avenue, St Louis, Missouri 63130, USA.;Laboratory of Parasitic Diseases, NIAID, National Institutes of Health, Bethesda, Maryland 20892, USA. [2] Department of Molecular Microbiology, Washington University School of Medicine, 660 S. Euclid Avenue, St Louis, Missouri 63130, USA.;Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rougea Louisian 70803, USA. [3] Department of Genetics, University of Georgia, Athens, Georgia 30602, USA.;Center for Tropical and Emerging Global Diseases, University of Georgia, Athens Georgia 30602, USA. [4] Program in Molecular Structure and Function, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1L7.;Departments of Biochemistry and Molecular Genetics, University of Toronto, Toronto, Ontario, Canada M5S 1A8. [5] Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. [6] Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK. [7] Biological Resource Center for Toxoplasma, INSERM, University Limoges, CHU Limoges, UMR_S 1094, Tropical Neuroepidemiology, Institute of Neuroepidemiology and Tropical Neurology, Limoges 87025, France. [8] Department of Microbiology and Immunology, Stanford School of Medicine, Stanford, California 94305, USA. [9] Department of Biological Sciences, Dietrich School of Arts and Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA. [10] Animal Parasitic Diseases Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service, USDA, Beltsville, Maryland 20705, USA. [11] Department of Veterinary Pathology and Microbiology, Washington State University, College of Veterinary Medicine, Pullman, Washington 99164, USA. [12] Department of Preventive Veterinary Medicine and Animal Health, Faculty of Veterinary Medicine, University of São Paulo, São Paulo, SP CEP 05598-270, Brazil. [13] Departments of Medicine, Pathology, and Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, USA. [14] Department of Pathology, Microbiology &Immunology, University of California, David, California 95616, USA. [15] Department of Microbiology, University of Tennessee, Knoxville, Tennessee 37996, USA. [16] Departments of Molecular Medicine and Global Health, Florida Center for Drug Discovery and Development (CDDI), University of South Florida, 3720 Spectrum Boulevard, Suite 304, Tampa, Florida 33612, USA. [17] State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, China. [18] Department of Veterinary Science, University of Kentucky, Lexington, Kentucky 40546, USA. [19] Laboratory of Parasitic Diseases, NIAID, National Institutes of Health, Bethesda, Maryland 20892, USA. [20] Department of Statistics, University of Georgia, Athens Georgia 30602, USA.;Institute of Bioinformatics, University of Georgia, Athens, Georgia 30602, USA. [21] Department of Genetics, University of Georgia, Athens, Georgia 30602, USA.;Center for Tropical and Emerging Global Diseases, University of Georgia, Athens Georgia 30602, USA.;Institute of Bioinformatics, University of Georgia, Athens, Georgia 30602, USA. [22] Department of Molecular Microbiology, Washington University School of Medicine, 660 S. Euclid Avenue, St Louis, Missouri 63130, USA. [23]
DOI 10.1038/ncomms10147
PMID 26738725
发布时间 2024-01-04
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