Goniothalamin induces cell cycle arrest and apoptosis in H400 human oral squamous cell carcinoma: A caspase-dependent mitochondrial-mediated pathway with downregulation of NF-κβ.-论文-万方医学网

作者： Lim K,Li ^[1] ; Ali-Saeed,Rola ^[2] ; Fahme A,Kaid ^[1] ; Abdul Manaf,Ali ^[2] ; Aied M,Alabsi ^[3]

作者单位： Department of Oral Biology and Biomedical Sciences, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia. ^[1] Faculty of Bioresource & Food Industry, University Sultan Zainal Abidin, 22200, Terengganu, Malaysia. ^[2] Department of Oral Biology and Biomedical Sciences, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia; Oral Cancer Research and Coordinating Centre,Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address: aied@um.edu.my. ^[3]

主题词抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);癌, 鳞状细胞(Carcinoma, Squamous Cell);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);细胞色素c类(Cytochromes c);胞质溶胶(Cytosol);减量调节(Down-Regulation);酶诱导(Enzyme Induction);头颈部肿瘤(Head and Neck Neoplasms);人类(Humans);膜电位, 线粒体(Membrane Potential, Mitochondrial);代谢网络和途径(Metabolic Networks and Pathways);线粒体(Mitochondria);口腔肿瘤(Mouth Neoplasms);NF-κB(NF-kappa B);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2);吡喃酮类(Pyrones);S期(S Phase)

DOI 10.1016/j.archoralbio.2015.12.002

PMID 26752226

发布时间 2019-02-21

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Goniothalamin induces cell cycle arrest and apoptosis in H400 human oral squamous cell carcinoma: A caspase-dependent mitochondrial-mediated pathway with downregulation of NF-κβ.

Archives of oral biology

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Goniothalamin induces cell cycle arrest and apoptosis in H400 human oral squamous cell carcinoma: A caspase-dependent mitochondrial-mediated pathway with downregulation of NF-κβ.

Archives of oral biology

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Archives of oral biology

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