Streptomycin treatment alters the intestinal microbiome, pulmonary T cell profile and airway hyperresponsiveness in a cystic fibrosis mouse model.

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作者： Mark,Bazett ^[1] ; Marie-Eve,Bergeron ^[2] ; Christina K,Haston ^[1]

作者单位： Meakins Christie Laboratories and the Department of Human Genetics, McGill University, Montreal, Quebec, Canada. ^[1] Meakins Christie Laboratories and the Department of Medicine, McGill University, Montreal, Quebec, Canada. ^[2]

主题词动物(Animals);抗菌药(Anti-Bacterial Agents);细菌载量(Bacterial Load);骨和骨组织(Bone and Bones);囊性纤维化(Cystic Fibrosis);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);免疫调节(Immunomodulation);免疫表型分型(Immunophenotyping);宏基因组(Metagenome);宏基因组学(Metagenomics);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 转基因(Mice, Transgenic);表型(Phenotype);呼吸超敏反应(Respiratory Hypersensitivity);链霉素(Streptomycin);T淋巴细胞亚群(T-Lymphocyte Subsets)

DOI 10.1038/srep19189

PMID 26754178

发布时间 2018-11-13

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Streptomycin treatment alters the intestinal microbiome, pulmonary T cell profile and airway hyperresponsiveness in a cystic fibrosis mouse model.

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Streptomycin treatment alters the intestinal microbiome, pulmonary T cell profile and airway hyperresponsiveness in a cystic fibrosis mouse model.

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