Abnormally activated one-carbon metabolic pathway is associated with mtDNA hypermethylation and mitochondrial malfunction in the oocytes of polycystic gilt ovaries.

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第一作者： Longfei,Jia

第一单位： Key Laboratory of Animal Physiology &Biochemistry, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, P. R. China.

作者： Longfei,Jia ^[1] ; Juan,Li ^[2] ; Bin,He ^[1] ; Yimin,Jia ^[1] ; Yingjie,Niu ^[2] ; Chenfei,Wang ^[2] ; Ruqian,Zhao ^[1]

作者单位： Key Laboratory of Animal Physiology &Biochemistry, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, P. R. China. ^[1] College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, P. R. China. ^[2] Jiangsu Collaborative Innovation Center of Meat Production and Processing, Quality and Safety Control, Nanjing 210095, P. R. China. ^[3]

主题词动物(Animals);碳(Carbon);DNA甲基化(DNA Methylation);DNA, 线粒体(DNA, Mitochondrial);女(雌)性(Female);鱼类(Fishes);基因剂量(Gene Dosage);基因表达调控(Gene Expression Regulation);基因, 线粒体(Genes, Mitochondrial);膜电位, 线粒体(Membrane Potential, Mitochondrial);代谢网络和途径(Metabolic Networks and Pathways);线粒体(Mitochondria);卵母细胞(Oocytes);多囊卵巢综合征(Polycystic Ovary Syndrome);蛋白质转运(Protein Transport);阻遏蛋白质类(Repressor Proteins)

DOI 10.1038/srep19436

PMID 26758245

发布时间 2018-11-13

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Abnormally activated one-carbon metabolic pathway is associated with mtDNA hypermethylation and mitochondrial malfunction in the oocytes of polycystic gilt ovaries.

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Abnormally activated one-carbon metabolic pathway is associated with mtDNA hypermethylation and mitochondrial malfunction in the oocytes of polycystic gilt ovaries.

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