Fibrotic Aortic Valve Stenosis in Hypercholesterolemic/Hypertensive Mice.

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作者： Yi,Chu ^[1] ; Donald D,Lund ^[1] ; Hardik,Doshi ^[1] ; Henry L,Keen ^[1] ; Kevin L,Knudtson ^[1] ; Nathan D,Funk ^[1] ; Jian Q,Shao ^[1] ; Justine,Cheng ^[1] ; Georges P,Hajj ^[1] ; Kathy A,Zimmerman ^[1] ; Melissa K,Davis ^[1] ; Robert M,Brooks ^[1] ; Mark W,Chapleau ^[1] ; Curt D,Sigmund ^[1] ; Robert M,Weiss ^[1] ; Donald D,Heistad ^[2]

作者单位： From the Departments of Internal Medicine (Y.C., D.D.L., H.D., N.D.F., J.C., G.P.H., K.A.Z., M.K.D., R.M.B., M.W.C., R.M.W., D.D.H.), Pharmacology (H.L.K., C.D.S., D.D.H.), Molecular Physiology and Biophysics (M.W.C.), Central Microscopy Research Facility (J.Q.S.), Iowa Institute of Human Genetics Genomics Division (K.L.K.), University of Iowa Carver College of Medicine, Iowa City; Veterans Administration Medical Center, Iowa City (M.W.C.); and Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder (D.D.H.). ^[1] From the Departments of Internal Medicine (Y.C., D.D.L., H.D., N.D.F., J.C., G.P.H., K.A.Z., M.K.D., R.M.B., M.W.C., R.M.W., D.D.H.), Pharmacology (H.L.K., C.D.S., D.D.H.), Molecular Physiology and Biophysics (M.W.C.), Central Microscopy Research Facility (J.Q.S.), Iowa Institute of Human Genetics Genomics Division (K.L.K.), University of Iowa Carver College of Medicine, Iowa City; Veterans Administration Medical Center, Iowa City (M.W.C.); and Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder (D.D.H.). donald-heistad@uiowa.edu. ^[2]

关键词 aortic valves constriction, pathologic hypercholesterolemia hypertension plasminogen activator inhibitor 1