Enabling personalized cancer medicine decisions: The challenging pharmacological approach of PBPK models for nanomedicine and pharmacogenomics (Review).

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作者： Ioannis S,Vizirianakis ^[1] ; George A,Mystridis ^[1] ; Konstantinos,Avgoustakis ^[2] ; Dimitrios G,Fatouros ^[3] ; Marios,Spanakis ^[4]

作者单位： Laboratory of Pharmacology, Department of Pharmaceutical Sciences, School of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki GR‑54124, Greece. ^[1] Laboratory of Pharmaceutical Technology, Department of Pharmaceutical Sciences, University of Patras, Patras GR-26504, Greece. ^[2] Laboratory of Pharmaceutical Technology, Department of Pharmaceutical Sciences, Aristotle University of Thessaloniki, Thessaloniki GR-54124, Greece. ^[3] Computational BioMedicine Laboratory, Institute of Computer Science, Foundation for Research and Technology-Hellas, Heraklion GR-71110, Crete, Greece. ^[4]

主题词化学, 药物(Chemistry, Pharmaceutical);健康知识, 态度, 实践(Health Knowledge, Attitudes, Practice);人类(Humans);模型, 生物学(Models, Biological);遗传药理学(Pharmacogenetics);药代动力学(Pharmacokinetics)

DOI 10.3892/or.2016.4575

PMID 26781205

发布时间 2016-12-30

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