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首页> Molecular biology and evolution> Contrasting Frequencies and Effects of cis- and trans-Regulatory Mutations Affecting Gene Expression.

Contrasting Frequencies and Effects of cis- and trans-Regulatory Mutations Affecting Gene Expression.

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作者： Brian P H,Metzger ^[1] ; Fabien,Duveau ^[1] ; David C,Yuan ^[2] ; Stephen,Tryban ^[1] ; Bing,Yang ^[3] ; Patricia J,Wittkopp ^[4]

作者单位： Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor. ^[1] Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor Department of Biology, Stanford University. ^[2] Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor. ^[3] Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor wittkopp@umich.edu. ^[4]

关键词 TDH3.distribution of mutational effects expression noise mutational target size neutral evolution

主题词等位基因(Alleles);碱基序列(Base Sequence);进化, 分子(Evolution, Molecular);基因表达(Gene Expression);基因表达调控, 真菌(Gene Expression Regulation, Fungal);遗传互补测验(Genetic Complementation Test);甘油醛-3-磷酸脱氢酶(磷酸化)(Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating));突变(Mutation);启动区, 遗传(Promoter Regions, Genetic);调控序列, 核酸(Regulatory Sequences, Nucleic Acid);酿酒酵母菌(Saccharomyces cerevisiae);酿酒酵母蛋白质类(Saccharomyces cerevisiae Proteins);遗传选择(Selection, Genetic)

DOI 10.1093/molbev/msw011

PMID 26782996

发布时间 2020-12-09

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Molecular biology and evolution

Molecular biology and evolution

2016年33卷5期

1131-46页

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