Medusamide A, a Panamanian Cyanobacterial Depsipeptide with Multiple β-Amino Acids.

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第一作者： Amanda M,Fenner

第一单位： Division of Medicinal Chemistry, Department of Pharmaceutical Sciences, University of Connecticut , Storrs, Connecticut 06269, United States.;Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego , La Jolla, California 92093, United States.;Instituto de Investigaciones Científicas y Servicios de Alta Tecnología (INDICASAT-AIP), City of Knowledge , Apartado 0816-02852, Panama City, Panama.;Smithsonian Tropical Research Institute (STRI) , Ancón, Apartado 0843-03092, Panama.

作者： Amanda M,Fenner ^[1] ; Niclas,Engene ^[2] ; Carmenza,Spadafora ^[3] ; William H,Gerwick ^[4] ; Marcy J,Balunas ^[5]

作者单位： Division of Medicinal Chemistry, Department of Pharmaceutical Sciences, University of Connecticut , Storrs, Connecticut 06269, United States.;Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego , La Jolla, California 92093, United States.;Instituto de Investigaciones Científicas y Servicios de Alta Tecnología (INDICASAT-AIP), City of Knowledge , Apartado 0816-02852, Panama City, Panama.;Smithsonian Tropical Research Institute (STRI) , Ancón, Apartado 0843-03092, Panama. ^[1] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego , La Jolla, California 92093, United States.;Department of Biological Sciences, Florida International University , Miami, Florida 33199, United States. ^[2] Instituto de Investigaciones Científicas y Servicios de Alta Tecnología (INDICASAT-AIP), City of Knowledge , Apartado 0816-02852, Panama City, Panama. ^[3] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego , La Jolla, California 92093, United States.;Smithsonian Tropical Research Institute (STRI) , Ancón, Apartado 0843-03092, Panama. ^[4] Division of Medicinal Chemistry, Department of Pharmaceutical Sciences, University of Connecticut , Storrs, Connecticut 06269, United States.;Instituto de Investigaciones Científicas y Servicios de Alta Tecnología (INDICASAT-AIP), City of Knowledge , Apartado 0816-02852, Panama City, Panama.;Smithsonian Tropical Research Institute (STRI) , Ancón, Apartado 0843-03092, Panama. ^[5]

主题词氰基细菌(Cyanobacteria);缩肽类(Depsipeptides);分子结构(Molecular Structure);核磁共振, 生物分子(Nuclear Magnetic Resonance, Biomolecular);巴拿马(Panama);立体异构现象(Stereoisomerism)

DOI 10.1021/acs.orglett.5b03110

PMID 26784681

发布时间 2019-05-08

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