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Impact of PEG and PEG-b-PAGE modified PLGA on nanoparticle formation, protein loading and release.

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第一作者： René,Rietscher

第一单位： Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Center for Infection Research (HZI), Saarland University, Saarbrücken, Germany.

作者： René,Rietscher ^[1] ; Justyna A,Czaplewska ^[2] ; Tobias C,Majdanski ^[2] ; Michael,Gottschaldt ^[2] ; Ulrich S,Schubert ^[2] ; Marc,Schneider ^[3] ; Claus-Michael,Lehr ^[4]

作者单位： Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Center for Infection Research (HZI), Saarland University, Saarbrücken, Germany. ^[1] Laboratory of Organic and Macromolecular Chemistry (IOMC) and Jena Center for Soft Matter (JCSM), Friedrich Schiller University, Jena, Germany. ^[2] Department of Pharmacy, Biopharmaceutics and Pharmaceutical Technology, Saarland University, Saarbrücken, Germany. ^[3] Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Center for Infection Research (HZI), Saarland University, Saarbrücken, Germany; Department of Pharmacy, Biopharmaceutics and Pharmaceutical Technology, Saarland University, Saarbrücken, Germany. Electronic address: claus-michael.lehr@helmholtz-hzi.de. ^[4]

关键词 Drug delivery Ovalbumin Poly(allyl glycidyl ether)Poly(d,l-lactic-co-glycolic acid)Polyethylene glycol Protein delivery