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首页> Methods in enzymology> Applying Thymine Isostere 2,4-Difluoro-5-Methylbenzene as a NMR Assignment Tool and Probe of Homopyrimidine/Homopurine Tract Structural Dynamics.

Applying Thymine Isostere 2,4-Difluoro-5-Methylbenzene as a NMR Assignment Tool and Probe of Homopyrimidine/Homopurine Tract Structural Dynamics.

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作者： Robert G,Brinson ^[1] ; Jennifer T,Miller ^[2] ; Jason D,Kahn ^[3] ; Stuart F J,Le Grice ^[2] ; John P,Marino ^[4]

作者单位： Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology and the University of Maryland, Rockville, Maryland, USA. Electronic address: brinson@ibbr.umd.edu. ^[1] Basic Research Laboratory, NCI-Frederick National Institutes of Health, Frederick, Maryland, USA. ^[2] Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland, USA. ^[3] Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology and the University of Maryland, Rockville, Maryland, USA. ^[4]

关键词 2,4-Difluoro-5-methylbenzene A-tracts High-resolution NMR Polypurine tract TATA box TATA box-binding protein

主题词碱基序列(Base Sequence);磁共振成像(Magnetic Resonance Imaging);核酸构象(Nucleic Acid Conformation);寡核苷酸类(Oligonucleotides);嘌呤类(Purines);嘧啶类(Pyrimidines);RNA(RNA);酿酒酵母菌(Saccharomyces cerevisiae);TATA盒(TATA Box);TATA盒结合蛋白质(TATA-Box Binding Protein)

DOI 10.1016/bs.mie.2015.05.009

PMID 26791977

发布时间 2019-10-08

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Methods in enzymology

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