PqsBC, a Condensing Enzyme in the Biosynthesis of the Pseudomonas aeruginosa Quinolone Signal: CRYSTAL STRUCTURE, INHIBITION, AND REACTION MECHANISM.
第一作者:
Steffen Lorenz,Drees
第一单位:
From the Institute for Molecular Microbiology and Biotechnology and.
作者:
医学主题词
3-氧酰基-(酰载体蛋白)合酶(3-Oxoacyl-(Acyl-Carrier-Protein) Synthase);4-喹诺酮类(4-Quinolones);苯乙酮类(Acetophenones);酰基辅酶A(Acyl Coenzyme A);氨基酸序列(Amino Acid Sequence);抗菌药(Anti-Bacterial Agents);细菌蛋白质类(Bacterial Proteins);结合部位(Binding Sites);结合, 竞争性(Binding, Competitive);生物催化(Biocatalysis);催化域(Catalytic Domain);结晶学, X线(Crystallography, X-Ray);酶抑制剂(Enzyme Inhibitors);大肠杆菌(Escherichia coli);动力学(Kinetics);配体(Ligands);模型, 分子(Models, Molecular);分子序列数据(Molecular Sequence Data);蛋白质结合(Protein Binding);蛋白质多聚化(Protein Multimerization);蛋白质结构, 二级(Protein Structure, Secondary);蛋白质亚单位(Protein Subunits);铜绿假单胞菌(Pseudomonas aeruginosa);重组蛋白质类(Recombinant Proteins);序列比对(Sequence Alignment)
DOI
10.1074/jbc.M115.708453
PMID
26811339
发布时间
2021-02-05
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