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首页> Genome research> A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening.

A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening.

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作者： Yarui,Diao ^[1] ; Bin,Li ^[1] ; Zhipeng,Meng ^[2] ; Inkyung,Jung ^[1] ; Ah Young,Lee ^[1] ; Jesse,Dixon ^[3] ; Lenka,Maliskova ^[4] ; Kun-Liang,Guan ^[2] ; Yin,Shen ^[4] ; Bing,Ren ^[5]

作者单位： Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, California 92093, USA; ^[1] Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, California 92093, USA; ^[2] Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, California 92093, USA; Medical Scientist Training Program, University of California, San Diego, La Jolla, California 92093, USA; Biomedical Sciences Graduate Program, University of California, San Diego, La Jolla, California 92093, USA; ^[3] Institute for Human Genetics and Department of Neurology, University of California, San Francisco, San Francisco, California 94143, USA; ^[4] Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, California 92093, USA; Department of Cellular and Molecular Medicine, Institute of Genomic Medicine and Moores Cancer Center, University of California, San Diego, La Jolla, California 92093, USA. ^[5]

主题词细胞系(Cell Line);增强子元件, 遗传学(Enhancer Elements, Genetic);基因表达调控(Gene Expression Regulation);基因打靶(Gene Targeting);基因检测(Genetic Testing);基因组, 人(Genome, Human);高通量筛选分析(High-Throughput Screening Assays);人类(Humans);八聚体转录因子3(Octamer Transcription Factor-3);表型(Phenotype);调控序列, 核酸(Regulatory Sequences, Nucleic Acid);序列缺失(Sequence Deletion)

DOI 10.1101/gr.197152.115

PMID 26813977

发布时间 2023-11-13

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Genome research

Genome research

2016年26卷3期

397-405页

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