Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells.

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作者： Joe,Nassour ^[1] ; Sébastien,Martien ^[1] ; Nathalie,Martin ^[1] ; Emeric,Deruy ^[1] ; Elisa,Tomellini ^[1] ; Nicolas,Malaquin ^[1] ; Fatima,Bouali ^[1] ; Laure,Sabatier ^[2] ; Nicolas,Wernert ^[3] ; Sébastien,Pinte ^[1] ; Eric,Gilson ^[4] ; Albin,Pourtier ^[4] ; Olivier,Pluquet ^[1] ; Corinne,Abbadie ^[1]

作者单位： Univ. Lille, CNRS, Institut Pasteur de Lille, UMR 8161 - M3T - Mechanisms of Tumorigenesis and Targeted Therapies, F-59000 Lille, France. ^[1] Commissariat à l'Energie Atomique (CEA), Laboratoire de Radiobiologie et Oncologie (LRO), 18 route du Panorama - BP6, 92265 Fontenay-aux-Roses 53011, France. ^[2] Institute of Pathology, University of Bonn, 53011 Bonn, Germany. ^[3] Institute for Research on Cancer and Aging, Nice (IRCAN), University of Nice Sophia Antipolis, CNRS, UMR7284, INSERM U108, Faculty of Medecine of Nice; CHU of Nice, Nice, France. ^[4]

主题词 DNA断裂, 单链(DNA Breaks, Single-Stranded);DNA损伤(DNA Damage);DNA修复(DNA Repair);DNA结合蛋白质类(DNA-Binding Proteins);上皮细胞(Epithelial Cells);人类(Humans);肿瘤(Neoplasms);聚ADP核糖聚合酶类(Poly(ADP-ribose) Polymerases)

DOI 10.1038/ncomms10399

PMID 26822533

发布时间 2018-11-13

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Nature communications

2016年7卷

10399页

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Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells.

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Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells.

Nature communications

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Nature communications

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