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Correctors of mutant CFTR enhance subcortical cAMP-PKA signaling through modulating ezrin phosphorylation and cytoskeleton organization.

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第一作者： Anna C,Abbattiscianni

第一单位： Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari 70126, Italy.

作者： Anna C,Abbattiscianni ^[1] ; Maria,Favia ^[1] ; Maria T,Mancini ^[1] ; Rosa A,Cardone ^[1] ; Lorenzo,Guerra ^[1] ; Stefania,Monterisi ^[2] ; Stefano,Castellani ^[3] ; Onofrio,Laselva ^[1] ; Francesca,Di Sole ^[4] ; Massimo,Conese ^[3] ; Manuela,Zaccolo ^[5] ; Valeria,Casavola ^[6]

作者单位： Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari 70126, Italy. ^[1] Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, UK. ^[2] Department of Medical and Surgical Sciences, University of Foggia, Foggia 71122, Italy. ^[3] Physiology and Pharmacology Department, Des Moines University, Des Moines, IA 50312, USA. ^[4] Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, UK valeria.casavola@uniba.it manuela.zaccolo@balliol.ox.ac.uk. ^[5] Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari 70126, Italy valeria.casavola@uniba.it manuela.zaccolo@balliol.ox.ac.uk. ^[6]

关键词 Airway cells Correctors Cystic fibrosis FRET PKA cAMP