mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts.-论文-万方医学网

作者： Vanni,Caruso ^[1] ; Smitha,Sreedharan ^[2] ; Valeria P,Carlini ^[3] ; Josefin A,Jacobsson ^[2] ; Tatjana,Haitina ^[2] ; Joanna,Hammer ^[2] ; Olga,Stephansson ^[2] ; Filip,Crona ^[2] ; Wolfgang H,Sommer ^[4] ; Ulf,Risérus ^[5] ; Lars,Lannfelt ^[6] ; Claude,Marcus ^[7] ; Markus,Heilig ^[8] ; Susana R,de Barioglio ^[9] ; Robert,Fredriksson ^[2] ; Helgi B,Schiöth ^[2]

作者单位： Department of Neuroscience, Unit of Functional Pharmacology, Uppsala University BMC, Uppsala SE 75124, Sweden; Faculty of Pharmacy, University of Tasmania (UTAS), 7001 Hobart, Australia. Electronic address: vanni.caruso@neuro.uu.se. ^[1] Department of Neuroscience, Unit of Functional Pharmacology, Uppsala University BMC, Uppsala SE 75124, Sweden. ^[2] Department of Neuroscience, Unit of Functional Pharmacology, Uppsala University BMC, Uppsala SE 75124, Sweden; Departamento de Farmacología, Facultad de Ciencias Químicas, Haya de la Torre y Medina Allende, Ciudad Universitaria, Universidad Nacional de Córdoba, 5016 Córdoba, Argentina. ^[3] Department of Psychopharmacology, Central Institute of Mental Health, Mannheim, Germany. ^[4] Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden. ^[5] Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden. ^[6] Department for Clinical Science, Intervention and Technology, Karolinska Institute, Division of Pediatrics, National Childhood Obesity Centre, Stockholm, Sweden. ^[7] Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA. ^[8] Departamento de Farmacología, Facultad de Ciencias Químicas, Haya de la Torre y Medina Allende, Ciudad Universitaria, Universidad Nacional de Córdoba, 5016 Córdoba, Argentina. ^[9]

主题词青少年(Adolescent);动物(Animals);脑(Brain);儿童(Child);进食(Eating);女(雌)性(Female);葡萄糖(Glucose);内环境稳定(Homeostasis);人类(Humans);男(雄)性(Male);中年人(Middle Aged);肥胖症(Obesity);多态性, 单核苷酸(Polymorphism, Single Nucleotide);RNA, 信使(RNA, Messenger);大鼠(Rats);大鼠, Wistar(Rats, Wistar);受体, G-蛋白偶联(Receptors, G-Protein-Coupled);种特异性(Species Specificity);瑞典(Sweden);组织分布(Tissue Distribution)

DOI 10.1016/j.gene.2016.01.044

PMID 26827797

发布时间 2016-02-24

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mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts.

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mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts.

Gene

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