Neuropathogenicity of Two Saffold Virus Type 3 Isolates in Mouse Models.-论文-万方医学网

第一作者： Osamu,Kotani

第一单位： Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan.

作者： Osamu,Kotani ^[1] ; Asif,Naeem ^[2] ; Tadaki,Suzuki ^[3] ; Naoko,Iwata-Yoshikawa ^[1] ; Yuko,Sato ^[1] ; Noriko,Nakajima ^[1] ; Takushi,Hosomi ^[1] ; Hiroyuki,Tsukagoshi ^[4] ; Kunihisa,Kozawa ^[5] ; Hideki,Hasegawa ^[5] ; Fumihiro,Taguchi ^[1] ; Hiroyuki,Shimizu ^[2] ; Noriyo,Nagata ^[3]

作者单位： Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan. ^[1] Department of Virology and Viral Infections, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, Tokyo, Japan. ^[2] Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan. ^[3] The Public Health Institute of Kochi Prefecture, Kochi, Japan. ^[4] Gunma Prefectural Institute of Public Health and Environmental Sciences, Gunma, Japan. ^[5]

主题词氨基酸序列(Amino Acid Sequence);动物(Animals);动物, 新生(Animals, Newborn);抗体, 中和(Antibodies, Neutralizing);抗原, 病毒(Antigens, Viral);体重(Body Weight);脑(Brain);心病毒属(Cardiovirus);心病毒感染(Cardiovirus Infections);脱髓鞘疾病(Demyelinating Diseases);疾病模型, 动物(Disease Models, Animal);疾病恶化(Disease Progression);女(雌)性(Female);免疫(Immunity);炎症(Inflammation);注射, 脑室内(Injections, Intraventricular);干扰素Ⅰ型(Interferon Type I);小鼠, 近交BALB C(Mice, Inbred BALB C);黏膜(Mucous Membrane);向性(Tropism);毒力(Virulence);病毒复制(Virus Replication)

DOI 10.1371/journal.pone.0148184

PMID 26828718

发布时间 2018-11-13

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Neuropathogenicity of Two Saffold Virus Type 3 Isolates in Mouse Models.

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Neuropathogenicity of Two Saffold Virus Type 3 Isolates in Mouse Models.

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