Bridging the Gap Between Science and Clinical Efficacy: Physiology, Imaging, and Modeling of Aerosols in the Lung.

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第一作者： Chantal,Darquenne

第一单位： 1 Department of Medicine, University of California , San Diego, La Jolla, California.

作者： Chantal,Darquenne ^[1] ; John S,Fleming ^[2] ; Ira,Katz ^[3] ; Andrew R,Martin ^[4] ; Jeffry,Schroeter ^[5] ; Omar S,Usmani ^[6] ; Jose,Venegas ^[7] ; Otmar,Schmid ^[8]

作者单位： 1 Department of Medicine, University of California , San Diego, La Jolla, California. ^[1] 2 National Institute of Health Research Biomedical Research Unit in Respiratory Disease , Southampton, United Kingdom .;3 Department of Medical Physics and Bioengineering, University Hospital Southampton NHS Foundation Trust , Southampton, United Kingdom . ^[2] 4 Medical R&D, Air Liquide Santé International, Centre de Recherche Paris-Saclay , Jouy-en-Josas, France .;5 Department of Mechanical Engineering, Lafayette College , Easton, Pennsylvania. ^[3] 6 Department of Mechanical Engineering, University of Alberta , Edmonton, Alberta, Canada . ^[4] 7 Applied Research Associates, Inc. , Raleigh, North Carolina. ^[5] 8 Airway Disease Section, National Heart and Lung Institute , Imperial College London and Royal Brompton Hospital, London, United Kingdom . ^[6] 9 Department of Anesthesia (Bioengineering), MGH/Harvard, Boston, Massachusetts. ^[7] 10 Comprehensive Pneumology Center (CPC), Member of the German Center for Lung Research , Munich, Germany .;11 Institute of Lung Biology and Disease, Helmholtz Zentrum München-German Research Center for Environmental Health , Neuherberg, Germany . ^[8]

关键词 PET SPECT aerosol deposition distribution biological lung models in-silico lung modeling