Psychological Stress Activates the Inflammasome via Release of Adenosine Triphosphate and Stimulation of the Purinergic Type 2X7 Receptor.

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第一作者： Masaaki,Iwata

第一单位： Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.

作者： Masaaki,Iwata ^[1] ; Kristie T,Ota ^[1] ; Xiao-Yuan,Li ^[1] ; Fumika,Sakaue ^[1] ; Nanxin,Li ^[1] ; Sophie,Dutheil ^[1] ; Mounira,Banasr ^[1] ; Vanja,Duric ^[2] ; Takehiko,Yamanashi ^[3] ; Koichi,Kaneko ^[3] ; Kurt,Rasmussen ^[4] ; Andrew,Glasebrook ^[4] ; Anja,Koester ^[4] ; Dekun,Song ^[5] ; Kenneth A,Jones ^[5] ; Stevin,Zorn ^[5] ; Gennady,Smagin ^[5] ; Ronald S,Duman ^[6]

作者单位： Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut. ^[1] Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut; Department of Physiology and Pharmacology, Des Moines University, Des Moines, Iowa. ^[2] Division of Neuropsychiatry, Tottori University, Tottori, Japan. ^[3] Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana. ^[4] Lundbeck Research USA, Paramus, New Jersey. ^[5] Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut. Electronic address: ronald.duman@yale.edu. ^[6]

关键词 ATP Depression IL-1β NLRP3 inflammasome P2X7 Stress