Effects of Anticancer Drugs on Chromosome Instability and New Clinical Implications for Tumor-Suppressing Therapies.

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作者： Hee-Sheung,Lee ^[1] ; Nicholas C O,Lee ^[1] ; Natalay,Kouprina ^[1] ; Jung-Hyun,Kim ^[1] ; Alex,Kagansky ^[2] ; Susan,Bates ^[1] ; Jane B,Trepel ^[1] ; Yves,Pommier ^[1] ; Dan,Sackett ^[3] ; Vladimir,Larionov ^[4]

作者单位： Developmental Therapeutics Branch, National Cancer Institute, NIH, Bethesda, Maryland. ^[1] Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland. ^[2] Program in Physical Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, Maryland. larionov@mail.nih.gov sackettd@mail.nih.gov. ^[3] Developmental Therapeutics Branch, National Cancer Institute, NIH, Bethesda, Maryland. larionov@mail.nih.gov sackettd@mail.nih.gov. ^[4]

主题词细胞系, 肿瘤(Cell Line, Tumor);细胞转化, 肿瘤(Cell Transformation, Neoplastic);染色体不稳定性(Chromosomal Instability);基因, 肿瘤抑制(Genes, Tumor Suppressor);人类(Humans);转基因(Transgenes)

DOI 10.1158/0008-5472.CAN-15-1617

PMID 26837770

发布时间 2024-06-10

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