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Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach.

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第一作者： L,Flanagan

第一单位： Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.;Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.

作者： L,Flanagan ^[1] ; M,Meyer ^[1] ; J,Fay ^[2] ; S,Curry ^[2] ; O,Bacon ^[3] ; H,Duessmann ^[4] ; K,John ^[5] ; K C,Boland ^[4] ; D A,McNamara ^[6] ; E W,Kay ^[2] ; H,Bantel ^[5] ; H,Schulze-Bergkamen ^[7] ; J H M,Prehn ^[1]

作者单位： Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.;Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland. ^[1] Department of Pathology, Beaumont Hospital, Dublin, Ireland. ^[2] Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.;Department of Surgery, Beaumont Hospital, Dublin, Ireland. ^[3] Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland. ^[4] Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany. ^[5] Department of Surgery, Beaumont Hospital, Dublin, Ireland. ^[6] Department of Medical Oncology, National Center for Tumor Diseases, Heidelberg, Germany.;Department of Gastroenterology and Oncology, Marien-Hospital Wesel, Wesel, Germany. ^[7]