Genetic basis of myeloid transformation in familial platelet disorder/acute myeloid leukemia patients with haploinsufficient RUNX1 allele.

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作者： M,Sakurai ^[1] ; H,Kasahara ^[1] ; K,Yoshida ^[2] ; A,Yoshimi ^[3] ; H,Kunimoto ^[1] ; N,Watanabe ^[4] ; Y,Shiraishi ^[5] ; K,Chiba ^[5] ; H,Tanaka ^[6] ; Y,Harada ^[7] ; H,Harada ^[7] ; T,Kawakita ^[8] ; M,Kurokawa ^[3] ; S,Miyano ^[5] ; S,Takahashi ^[6] ; S,Ogawa ^[8] ; S,Okamoto ^[2] ; H,Nakajima ^[1]

作者单位： Division of Hematology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan. ^[1] Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. ^[2] Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. ^[3] Department of Transfusion Medicine & Cell Therapy, Keio University School of Medicine, Tokyo, Japan. ^[4] Laboratory of DNA Information Analysis, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. ^[5] Laboratory of Sequence Analysis, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. ^[6] Department of Hematology, Juntendo University School of Medicine, Tokyo, Japan. ^[7] Department of Hematology/Oncology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. ^[8]

主题词成年人(Adult);等位基因(Alleles);血小板疾病(Blood Platelet Disorders);细胞转化, 肿瘤(Cell Transformation, Neoplastic);核心结合因子α2亚基(Core Binding Factor Alpha 2 Subunit);女(雌)性(Female);遗传关联研究(Genetic Association Studies);疾病遗传易感性(Genetic Predisposition to Disease);单倍剂量不足(Haploinsufficiency);人类(Humans);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);男(雄)性(Male);中年人(Middle Aged);系谱(Pedigree)

DOI 10.1038/bcj.2015.81

PMID 26849013

发布时间 2018-11-13

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Blood cancer journal

2016年6卷

e392页

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Genetic basis of myeloid transformation in familial platelet disorder/acute myeloid leukemia patients with haploinsufficient RUNX1 allele.

Blood cancer journal

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Blood cancer journal

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Genetic basis of myeloid transformation in familial platelet disorder/acute myeloid leukemia patients with haploinsufficient RUNX1 allele.

Blood cancer journal

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Blood cancer journal

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