Degradation Kinetics and Mechanism of a β-Lactam Antibiotic Intermediate, 6-Aminopenicillanic Acid, in a New Integrated Production Process.

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作者： Min,Su ^[1] ; Hua,Sun ^[2] ; Yingying,Zhao ^[3] ; Aidang,Lu ^[4] ; Xiaohui,Cao ^[5] ; Jingkang,Wang ^[6]

作者单位： School of Marine Science and Engineering, Hebei University of Technology, Tianjin 300130, China; State Research Center of Industrialization for Crystallization Technology, School of Chemical Engineering and technology, Tianjin University, Tianjin 300072, China; School of Chemical Engineering, Hebei University of Technology, Tianjin 300130, China. Electronic address: sumin@tju.edu.cn. ^[1] College of Chemical and Pharmaceutical Engineering, Hebei Universtity of Science and Technology, Shijiazhuang 050018, China; State Research Center of Industrialization for Crystallization Technology, School of Chemical Engineering and technology, Tianjin University, Tianjin 300072, China. ^[2] School of Marine Science and Engineering, Hebei University of Technology, Tianjin 300130, China; State Research Center of Industrialization for Crystallization Technology, School of Chemical Engineering and technology, Tianjin University, Tianjin 300072, China. ^[3] School of Marine Science and Engineering, Hebei University of Technology, Tianjin 300130, China. ^[4] School of Chemical Engineering, Hebei University of Technology, Tianjin 300130, China. ^[5] State Research Center of Industrialization for Crystallization Technology, School of Chemical Engineering and technology, Tianjin University, Tianjin 300072, China. ^[6]

关键词 chemical stability degradation products kinetics processing unit operations