Immunization with a 22-kDa outer membrane protein elicits protective immunity to multidrug-resistant Acinetobacter baumannii.

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作者： Weiwei,Huang ^[1] ; Yufeng,Yao ^[2] ; Shijie,Wang ^[3] ; Ye,Xia ^[1] ; Xu,Yang ^[2] ; Qiong,Long ^[3] ; Wenjia,Sun ^[1] ; Cunbao,Liu ^[2] ; Yang,Li ^[3] ; Xiaojie,Chu ^[1] ; Hongmei,Bai ^[2] ; Yueting,Yao ^[3] ; Yanbing,Ma ^[1]

作者单位： Laboratory of Molecular Immunology, Institute of Medical Biology, Chinese Academy of Medical Sciences &Peking Union Medical College; Kunming, China 650118. ^[1] Yunnan Key Laboratory of Vaccine Research &Development on Severe Infectious Diseases; Kunming, China 650118. ^[2] Yunnan Engineering Research Center of Vaccine Research and Development on Severe Infectious Diseases, Kunming, China 650118. ^[3]

主题词不动杆菌感染(Acinetobacter Infections);鲍氏不动杆菌(Acinetobacter baumannii);动物结构(Animal Structures);动物(Animals);抗体, 细菌(Antibodies, Bacterial);抗原, 细菌(Antigens, Bacterial);细菌载量(Bacterial Load);细菌外膜蛋白质类(Bacterial Outer Membrane Proteins);细菌菌苗(Bacterial Vaccines);血液(Blood);补体系统蛋白质类(Complement System Proteins);保守序列(Conserved Sequence);细胞因子类(Cytokines);疾病模型, 动物(Disease Models, Animal);药物评价, 临床前(Drug Evaluation, Preclinical);抗药性, 多种, 细菌(Drug Resistance, Multiple, Bacterial);女(雌)性(Female);免疫法, 被动(Immunization, Passive);免疫球蛋白G(Immunoglobulin G);小鼠, 近交ICR(Mice, Inbred ICR);分子量(Molecular Weight);吞噬作用(Phagocytosis);重组蛋白质类(Recombinant Proteins);血清(Serum);存活率分析(Survival Analysis);接种(Vaccination);疫苗, 亚单位(Vaccines, Subunit);疫苗, 合成(Vaccines, Synthetic)

DOI 10.1038/srep20724

PMID 26853590

发布时间 2018-11-13

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Immunization with a 22-kDa outer membrane protein elicits protective immunity to multidrug-resistant Acinetobacter baumannii.

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Immunization with a 22-kDa outer membrane protein elicits protective immunity to multidrug-resistant Acinetobacter baumannii.

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