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首页> Pediatric research> Smad7 interrupts TGF-β signaling in intestinal macrophages and promotes inflammatory activation of these cells during necrotizing enterocolitis.

Smad7 interrupts TGF-β signaling in intestinal macrophages and promotes inflammatory activation of these cells during necrotizing enterocolitis.

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第一作者： Krishnan,MohanKumar

第一单位： Department of Pediatrics, University of Illinois at Chicago, Chicago, Illinois.

作者： Krishnan,MohanKumar ^[1] ; Kopperuncholan,Namachivayam ^[2] ; Kalyan C,Chapalamadugu ^[1] ; Steven A,Garzon ^[2] ; Muralidhar H,Premkumar ^[3] ; Srinivas M,Tipparaju ^[4] ; Akhil,Maheshwari ^[5]

作者单位： Department of Pediatrics, University of Illinois at Chicago, Chicago, Illinois. ^[1] Department of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, Florida. ^[2] Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, Florida. ^[3] Department of Pathology, University of Illinois at Chicago, Chicago, Illinois. ^[4] Department of Pediatrics, Baylor College of Medicine, Houston, Texas. ^[5] Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida. ^[6] Department of Community and Family Health, College of Public Health, University of South Florida, Tampa, Florida. ^[7]

主题词动物(Animals);小肠结肠炎, 坏死性(Enterocolitis, Necrotizing);人类(Humans);I-κB激酶(I-kappa B Kinase);炎症(Inflammation);肠黏膜(Intestinal Mucosa);脂多糖类(Lipopolysaccharides);巨噬细胞(Macrophages);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);NF-κB(NF-kappa B);信号传导(Signal Transduction);Smad7蛋白质(Smad7 Protein);转化生长因子β(Transforming Growth Factor beta)

DOI 10.1038/pr.2016.18

PMID 26859364

发布时间 2018-12-02

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Pediatric research

Pediatric research

2016年79卷6期

951-61页

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