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A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors.

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第一作者： Marina,Bacac

第一单位： Oncology Discovery, Roche Innovation Center Zurich, Roche Pharmaceutical Research and Early Development, pRED, Zurich, Switzerland. marina.bacac@roche.com Pablo.umana@roche.com.

作者： Marina,Bacac ^[1] ; Tanja,Fauti ^[2] ; Johannes,Sam ^[2] ; Sara,Colombetti ^[2] ; Tina,Weinzierl ^[2] ; Djamila,Ouaret ^[3] ; Walter,Bodmer ^[3] ; Steffi,Lehmann ^[4] ; Thomas,Hofer ^[5] ; Ralf J,Hosse ^[5] ; Ekkehard,Moessner ^[5] ; Oliver,Ast ^[5] ; Peter,Bruenker ^[5] ; Sandra,Grau-Richards ^[5] ; Teilo,Schaller ^[2] ; Annette,Seidl ^[6] ; Christian,Gerdes ^[2] ; Mario,Perro ^[2] ; Valeria,Nicolini ^[2] ; Nathalie,Steinhoff ^[2] ; Sherri,Dudal ^[7] ; Sebastian,Neumann ^[8] ; Thomas,von Hirschheydt ^[9] ; Christiane,Jaeger ^[5] ; Jose,Saro ^[10] ; Vaios,Karanikas ^[10] ; Christian,Klein ^[2] ; Pablo,Umaña ^[1]

作者单位： Oncology Discovery, Roche Innovation Center Zurich, Roche Pharmaceutical Research and Early Development, pRED, Zurich, Switzerland. marina.bacac@roche.com Pablo.umana@roche.com. ^[1] Oncology Discovery, Roche Innovation Center Zurich, Roche Pharmaceutical Research and Early Development, pRED, Zurich, Switzerland. ^[2] Cancer and Immunogenetics Laboratory, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom. ^[3] Animal Imaging Center, Institute for Biomedical Engineering, ETH and University of Zurich, Zurich, Switzerland. ^[4] Large Molecule Research, Roche Innovation Center Zurich, Roche Pharmaceutical Research and Early Development, pRED, Zurich, Switzerland. ^[5] Roche Diagnostics GmbH, Penzberg, Germany. ^[6] Pharmaceutical Sciences, Roche Innovation Center Basel, Basel, Switzerland. ^[7] Global Technical Development Project Management, F. Hoffmann-La Roche AG, Basel, Switzerland. ^[8] Large Molecule Research, Roche Innovation Center Penzberg, Germany. ^[9] Translational Medicine, Roche Innovation Center Zurich, Zurich, Switzerland. ^[10]