NK Cell-Mediated Antitumor Effects of a Folate-Conjugated Immunoglobulin Are Enhanced by Cytokines.-论文-万方医学网

作者： Alena C,Jaime-Ramirez ^[1] ; Elizabeth,McMichael ^[2] ; SriVidya,Kondadasula ^[3] ; Cassandra C,Skinner ^[4] ; Bethany L,Mundy-Bosse ^[5] ; Eric,Luedke ^[4] ; Natalie B,Jones ^[6] ; Aruna,Mani ^[7] ; Julie,Roda ^[8] ; Volodymyr,Karpa ^[9] ; Hong,Li ^[10] ; Jilong,Li ^[10] ; Saranya,Elavazhagan ^[11] ; Krista M,La Perle ^[12] ; Alessandra C,Schmitt ^[13] ; Yanhui,Lu ^[14] ; Xiaoli,Zhang ^[15] ; Xueliang,Pan ^[15] ; Hsaioyin,Mao ^[5] ; Melanie,Davis ^[16] ; David,Jarjoura ^[15] ; Jonathan P,Butchar ^[11] ; Ming,Poi ^[10] ; Mitch,Phelps ^[10] ; Susheela,Tridandapani ^[11] ; John C,Byrd ^[16] ; Michael A,Caligiuri ^[5] ; Robert J,Lee ^[10] ; William E,Carson ^[2]

作者单位： Department of Neurosurgery, The Ohio State University, Columbus, OH. ^[1] Department of Biomedical Sciences Graduate Program, College of Medicine, The Ohio State University, Columbus, OH. ^[2] Karmanos Cancer Institute, Detroit, MI. ^[3] Department of Surgery, The Ohio State University, Columbus, OH. ^[4] Arthur G. James Comprehensive Cancer Center and Solove Research Institute, The Ohio State University, Columbus, OH. ^[5] Riverside Breast Specialists, Westerville, OH. ^[6] Breast Cancer Center, Memorial Cancer Institute, Pembroke Pines, FL. ^[7] OncoMed Pharmaceuticals Inc., Redwood City, CA. ^[8] Wright State University School of Medicine, Dayton, OH. ^[9] College of Pharmacy, The Ohio State University, Columbus, OH. ^[10] Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Internal Medicine, The Ohio State University, Columbus, OH. ^[11] Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH. ^[12] Grady Memorial Hospital, Atlanta, GA. ^[13] Merck & Co, Kenilworth, NJ. ^[14] Center for Biostatistics, The Ohio State University, Columbus, OH. ^[15] Division of Hematology, The Ohio State University, Columbus, OH. ^[16]

主题词动物(Animals);抗体依赖细胞细胞毒性(Antibody-Dependent Cell Cytotoxicity);细胞系, 肿瘤(Cell Line, Tumor);细胞因子类(Cytokines);细胞毒性, 免疫(Cytotoxicity, Immunologic);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);叶酸盐受体1(Folate Receptor 1);叶酸(Folic Acid);基因表达(Gene Expression);人类(Humans);免疫轭合物(Immunoconjugates);免疫球蛋白G(Immunoglobulin G);免疫调节(Immunomodulation);白细胞介素12(Interleukin-12);杀伤细胞, 天然(Killer Cells, Natural);淋巴细胞活化(Lymphocyte Activation);小鼠(Mice);单核细胞(Monocytes);肿瘤(Neoplasms);肿瘤负荷(Tumor Burden);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1158/2326-6066.CIR-15-0168

PMID 26865456

发布时间 2018-11-13

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NK Cell-Mediated Antitumor Effects of a Folate-Conjugated Immunoglobulin Are Enhanced by Cytokines.

Cancer immunology research

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Cancer immunology research

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NK Cell-Mediated Antitumor Effects of a Folate-Conjugated Immunoglobulin Are Enhanced by Cytokines.

Cancer immunology research

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Cancer immunology research

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