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首页> Chemico-biological interactions> Anticancer activity and radiosensitization effect of methyleneisoxazolidin-5-ones in hepatocellular carcinoma HepG2 cells.

Anticancer activity and radiosensitization effect of methyleneisoxazolidin-5-ones in hepatocellular carcinoma HepG2 cells.

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作者： Katarzyna,Gach ^[1] ; Iwona,Grądzka ^[2] ; Iwona,Wasyk ^[2] ; Sylwia,Męczyńska-Wielgosz ^[2] ; Teresa,Iwaneńko ^[2] ; Jacek,Szymański ^[3] ; Jacek,Koszuk ^[4] ; Tomasz,Janecki ^[4] ; Marcin,Kruszewski ^[5] ; Anna,Janecka ^[6]

作者单位： Department of Biomolecular Chemistry, Faculty of Medicine, Medical University of Lodz, Lodz, Poland. ^[1] Center for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Warsaw, Poland. ^[2] Central Scientific Laboratory, Division of Public Health, Faculty of Health Sciences, Medical University of Lodz, Lodz, Poland. ^[3] Institute of Organic Chemistry, Lodz University of Technology, Lodz, Poland. ^[4] Center for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Warsaw, Poland; Faculty of Medicine, University of Information Technology and Management, Rzeszów, Poland. ^[5] Department of Biomolecular Chemistry, Faculty of Medicine, Medical University of Lodz, Lodz, Poland. Electronic address: anna.janecka@umed.lodz.pl. ^[6]

关键词 Anticancer agents Apoptosis HepG2 Integrated therapy X-ray sensitization

主题词消炎药, 非甾类(Anti-Inflammatory Agents, Non-Steroidal);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);细胞存活(Cell Survival);DNA损伤(DNA Damage);Hep G2细胞(Hep G2 Cells);人类(Humans);异恶唑类(Isoxazoles);膜电位, 线粒体(Membrane Potential, Mitochondrial);辐射增敏药(Radiation-Sensitizing Agents);活性氧(Reactive Oxygen Species);倍半萜类(Sesquiterpenes)

DOI 10.1016/j.cbi.2016.01.011

PMID 26867810

发布时间 2016-03-11

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Chemico-biological interactions

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