首页> Oncotarget> Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSA-/lo castration-resistant cells.

Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSA-/lo castration-resistant cells.

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第一作者： Kiera,Rycaj

第一单位： Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Smithville, TX 78957, USA.

作者： Kiera,Rycaj ^[1] ; Eun Jeong,Cho ^[2] ; Xin,Liu ^[1] ; Hsueh-Ping,Chao ^[1] ; Bigang,Liu ^[1] ; Qiuhui,Li ^[1] ; Ashwini K,Devkota ^[2] ; Dingxiao,Zhang ^[1] ; Xin,Chen ^[1] ; John,Moore ^[1] ; Kevin N,Dalby ^[2] ; Dean G,Tang ^[3]

作者单位： Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Smithville, TX 78957, USA. ^[1] College of Pharmacy, Targeted Therapeutic Drug Discovery and Development Core Facility (TTDDD), The University of Texas at Austin, Austin, TX 78712, USA. ^[2] Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Smithville, TX 78957, USA.;Cancer Stem Cell Institute, Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China.;Centers for Cancer Epigenetics, Stem Cell and Developmental Biology, RNA Interference and Non-coding RNAs, and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. ^[3]

关键词 cancer stem cells castration resistance cellular heterogeneity differentiation prostate cancer