Contribution of PPARα/β/γ, AP-1, importin-α3, and RXRα to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against hypotension, tachycardia, and inflammation in a rat model of septic shock.-论文-万方医学网

作者： Sefika Pinar,Senol ^[1] ; Meryem,Temiz ^[1] ; Demet Sinem,Guden ^[1] ; Pelin,Cecen ^[1] ; Ayse Nihal,Sari ^[1] ; Seyhan,Sahan-Firat ^[1] ; John R,Falck ^[2] ; Rambabu,Dakarapu ^[2] ; Kafait U,Malik ^[3] ; Bahar,Tunctan ^[4]

作者单位： Department of Pharmacology, Faculty of Pharmacy, Yenisehir Campus, Mersin University, 33169, Mersin, Turkey. ^[1] Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA. ^[2] Department of Pharmacology, College of Medicine, Center for Health Sciences, University of Tennessee, Memphis, TN, USA. ^[3] Department of Pharmacology, Faculty of Pharmacy, Yenisehir Campus, Mersin University, 33169, Mersin, Turkey. btunctan@gmail.com. ^[4]

主题词动物(Animals);消炎药(Anti-Inflammatory Agents);主动脉, 胸(Aorta, Thoracic);疾病模型, 动物(Disease Models, Animal);羟基花生四烯酸类(Hydroxyeicosatetraenoic Acids);低血压(Hypotension);肾(Kidney);脂肽类(Lipopeptides);脂多糖类(Lipopolysaccharides);男(雄)性(Male);肠系膜动脉(Mesenteric Arteries);心肌(Myocardium);PPARα(PPAR alpha);PPARγ(PPAR gamma);PPARβ(PPAR-beta);大鼠, Wistar(Rats, Wistar);维甲类X受体α(Retinoid X Receptor alpha);休克, 脓毒性(Shock, Septic);心动过速(Tachycardia);转录因子AP-1(Transcription Factor AP-1);α核胞浆转运蛋白类(alpha Karyopherins)

DOI 10.1007/s00011-016-0922-5

PMID 26875149

发布时间 2020-06-12

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Contribution of PPARα/β/γ, AP-1, importin-α3, and RXRα to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against hypotension, tachycardia, and inflammation in a rat model of septic shock.

Inflammation research

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Contribution of PPARα/β/γ, AP-1, importin-α3, and RXRα to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against hypotension, tachycardia, and inflammation in a rat model of septic shock.

Inflammation research

相似文献

Inflammation research

相关期刊

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