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首页> Human psychopharmacology> Genetic association analysis of N-methyl-D-aspartate receptor subunit gene GRIN2B and clinical response to clozapine.

Genetic association analysis of N-methyl-D-aspartate receptor subunit gene GRIN2B and clinical response to clozapine.

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作者： Danielle L,Taylor ^[1] ; Arun K,Tiwari ^[2] ; Jeffrey A,Lieberman ^[1] ; Steven G,Potkin ^[3] ; Herbert Y,Meltzer ^[4] ; Jo,Knight ^[5] ; Gary,Remington ^[1] ; Daniel J,Müller ^[2] ; James L,Kennedy ^[6]

作者单位： Neurogenetics Section, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada. ^[1] Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada. ^[2] Department of Psychiatry, College of Physicians and Surgeons, Columbia University and the New York State Psychiatric Institute, New York City, New York, USA. ^[3] Department of Psychiatry, University of California, Irvine, Irvine, California, USA. ^[4] Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. ^[5] Department of Psychiatry, University of Toronto, Toronto, ON, Canada. ^[6] Schizophrenia Program, Centre for Addiction and Mental Health, Toronto, ON, Canada. ^[7]

关键词 GRIN2B clozapine glutamate pharmacogenetics schizophrenia

主题词成年人(Adult);抗精神病药(Antipsychotic Agents);氯氮平(Clozapine);抗药性(Drug Resistance);女(雌)性(Female);遗传关联研究(Genetic Association Studies);单倍型(Haplotypes);人类(Humans);连锁不平衡(Linkage Disequilibrium);男(雄)性(Male);多态性, 单核苷酸(Polymorphism, Single Nucleotide);精神病状态评定量表(Psychiatric Status Rating Scales);受体, N-甲基-D-天冬氨酸(Receptors, N-Methyl-D-Aspartate);精神分裂症(Schizophrenia);治疗结果(Treatment Outcome)

DOI 10.1002/hup.2519

PMID 26876050

发布时间 2022-12-07

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Human psychopharmacology

Human psychopharmacology

2016年31卷2期

121-34页

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