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Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival.

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第一作者： Jason G,Kettle

第一单位： Oncology Innovative Medicines Unit, AstraZeneca , 35S47 Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom.

作者： Jason G,Kettle ^[1] ; Husam,Alwan ^[1] ; Michal,Bista ^[2] ; Jason,Breed ^[3] ; Nichola L,Davies ^[2] ; Kay,Eckersley ^[4] ; Shaun,Fillery ^[2] ; Kevin M,Foote ^[2] ; Louise,Goodwin ^[1] ; David R,Jones ^[1] ; Helena,Käck ^[5] ; Alan,Lau ^[1] ; J Willem M,Nissink ^[2] ; Jon,Read ^[3] ; James S,Scott ^[2] ; Ben,Taylor ^[3] ; Graeme,Walker ^[4] ; Lisa,Wissler ^[5] ; Marta,Wylot ^[2]

作者单位： Oncology Innovative Medicines Unit, AstraZeneca , 35S47 Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom. ^[1] Oncology Innovative Medicines Unit, AstraZeneca , Unit 310, Darwin Building, Cambridge Science Park, Milton Road, Cambridge CB4 0WG, United Kingdom. ^[2] Discovery Sciences, AstraZeneca , Unit 310, Darwin Building, Cambridge Science Park, Milton Road, Cambridge CB4 0WG, United Kingdom. ^[3] Discovery Sciences, AstraZeneca , Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom. ^[4] Discovery Sciences, AstraZeneca , Pepparedsleden 1, 431 83 Mölndal, Sweden. ^[5]