Immunization of A4galt-deficient mice with glycosphingolipids from renal cell cancers resulted in the generation of anti-sulfoglycolipid monoclonal antibodies.

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第一作者： Reiko,Ando

第一单位： Department of Biochemistry II, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, 466-0065, Japan.

作者： Reiko,Ando ^[1] ; Noriyo,Tokuda ^[1] ; Tokunori,Yamamoto ^[2] ; Kazutaka,Ikeda ^[3] ; Noboru,Hashimoto ^[1] ; Ryo,Taguchi ^[4] ; Xiaoen,Fan ^[1] ; Keiko,Furukawa ^[1] ; Yukio,Niimura ^[4] ; Akemi,Suzuki ^[5] ; Momokazu,Goto ^[6] ; Koichi,Furukawa ^[2]

作者单位： Department of Biochemistry II, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, 466-0065, Japan. ^[1] Department of Urology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, 466-0065, Japan. ^[2] IMS, RIKEN Center for Integrative Medical Sciences, 1-7-22, Suehiro, Tsurumi-ku, Yokohama, 230-0045, Japan. ^[3] Department of Biomedical Sciences, Chubu University College of Life and Health Sciences, 1200 Matsumoto, Kasugai, Aichi, 487-8501, Japan. ^[4] Research Center of Biomedical Analysis and Radioisotope, Teikyo University School of Medicine, 2-11-1, Kuga, Itabashi-ku, Tokyo, 173-8605, Japan. ^[5] Institute of Glycoscience, Tokai University, 4-1-1 Kitakaname, Hiratsuka, Kanagawa, 259-1292, Japan. ^[6] Department of Biochemistry II, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, 466-0065, Japan. koichi@med.nagoya-u.ac.jp. ^[7] Department of Biomedical Sciences, Chubu University College of Life and Health Sciences, 1200 Matsumoto, Kasugai, Aichi, 487-8501, Japan. koichi@med.nagoya-u.ac.jp. ^[8]

关键词 A4galt Kidney Monoclonal antibody Renal cell cancer Sulfoglycolipid