Characterization and In Vitro Evaluation of the Complexes of Posaconazole with β- and 2,6-di-O-methyl-β-cyclodextrin.

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第一作者： Peixiao,Tang

第一单位： College of Chemical Engineering, Sichuan University, Chengdu, 610065, China.

作者： Peixiao,Tang ^[1] ; Lei,Wang ^[2] ; Xiaoli,Ma ^[1] ; Kailin,Xu ^[1] ; Xinnuo,Xiong ^[1] ; Xiaoxiang,Liao ^[1] ; Hui,Li ^[3]

作者单位： College of Chemical Engineering, Sichuan University, Chengdu, 610065, China. ^[1] Sichuan Guang'an Food and Drug Administration, Guang'an, 638000, China. ^[2] College of Chemical Engineering, Sichuan University, Chengdu, 610065, China. lihuilab@sina.com. ^[3]

关键词 characterization cyclodextrin in vitro antifungal testing inclusion complex posaconazole

主题词抗真菌药(Antifungal Agents);量热法, 差式扫描(Calorimetry, Differential Scanning);溶解度(Solubility);谱学, 傅里叶变换红外(Spectroscopy, Fourier Transform Infrared);三唑类(Triazoles);水(Water);β环糊精类(beta-Cyclodextrins)

DOI 10.1208/s12249-016-0497-z

PMID 26883260

发布时间 2017-01-23

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