Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model.-论文-万方医学网

第一作者： Yuki,Narita

第一单位： Center for Clinical Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto, 862-0973, Japan.

作者： Yuki,Narita ^[1] ; Miki,Ueda ^[2] ; Kohei,Uchimura ^[3] ; Yutaka,Kakizoe ^[2] ; Yoshikazu,Miyasato ^[2] ; Teruhiko,Mizumoto ^[2] ; Jun,Morinaga ^[2] ; Manabu,Hayata ^[2] ; Terumasa,Nakagawa ^[2] ; Masataka,Adachi ^[2] ; Taku,Miyoshi ^[2] ; Yoshiki,Sakai ^[4] ; Daisuke,Kadowaki ^[1] ; Sumio,Hirata ^[1] ; Masashi,Mukoyama ^[2] ; Kenichiro,Kitamura ^[5]

作者单位： Center for Clinical Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto, 862-0973, Japan. ^[1] Department of Nephrology, Kumamoto University Graduate School of Medical Sciences, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan. ^[2] Department of Internal Medicine III, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo-shi, Yamanashi, 409-3898, Japan. ^[3] Research Headquarters, Ono Pharmaceutical Co., Ltd., 1-8-2 Kyutaromachi, Chuo-ku, Osaka, 541-8564, Japan. ^[4] Department of Internal Medicine III, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo-shi, Yamanashi, 409-3898, Japan. Electronic address: kkenichiro@yamanashi.ac.jp. ^[5]

主题词醛固酮(Aldosterone);血管紧张素Ⅱ1型受体拮抗剂(Angiotensin II Type 1 Receptor Blockers);动物(Animals);抗高血压药(Antihypertensive Agents);苯咪唑类(Benzimidazoles);苯甲酸盐类(Benzoates);血压(Blood Pressure);肌酸酐(Creatinine);疾病模型, 动物(Disease Models, Animal);药物疗法, 联合(Drug Therapy, Combination);酯类(Esters);纤维化(Fibrosis);加贝酯(Gabexate);胍类(Guanidines);肾(Kidney);男(雄)性(Male);氧化性应激(Oxidative Stress);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);肾功能不全, 慢性(Renal Insufficiency, Chronic);肾素(Renin);肾素-血管紧张素系统(Renin-Angiotensin System);丝氨酸蛋白酶抑制剂(Serine Proteinase Inhibitors)

DOI 10.1016/j.jphs.2016.01.003

PMID 26887332

发布时间 2021-12-03

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Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model.

Journal of pharmacological sciences

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Journal of pharmacological sciences

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Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model.

Journal of pharmacological sciences

相似文献

Journal of pharmacological sciences

相关期刊

检索历史清除