Imaging and serum biomarkers reflecting the functional efficacy of extended erythropoietin treatment in rats following infantile traumatic brain injury.
第一作者:
Shenandoah,Robinson
第一单位:
Brain Injury Center and ;Departments of 2 Neurosurgery.;Neurology.;F. M. Kirby Center for Neurobiology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts; and
作者:
关键词
AD = axial diffusivityCCI = controlled cortical impactCXCL1 = chemokine (CXC) ligand 1DP = degradation productDTI = diffusion tensor imagingEP = echo planarEPO = erythropoietinEPOR = EPO receptorFA = fractional anisotropyGFAP = glial fibrillary acidic proteinIFNγ = interferon gammaIL = interleukinKCC2 = potassium chloride cotransporter 2MD = mean diffusivityMECI = multielectrochemiluminescenceP = postnatal dayPID = postinjury dayRD = radial diffusivityROI = region of interestSWI = susceptibility-weighted imagingTBI = traumatic brain injuryTNFα = tumor necrosis factor alphacontrolled cortical impactdiffusion tensor imagingdiffusivityerythropoietininfantserum biomarkertraumatraumatic brain injuryveh = vehicleαII-SDPs = αII-spectrin DPs
医学主题词
年龄因素(Age Factors);动物(Animals);动物, 新生(Animals, Newborn);卡配因(Calpain);大脑皮质(Cerebral Cortex);细胞因子类(Cytokines);弥散磁共振成像(Diffusion Magnetic Resonance Imaging);疾病模型, 动物(Disease Models, Animal);红细胞生成素α(Epoetin Alfa);红细胞生成素(Erythropoietin);女(雌)性(Female);步态障碍, 神经性(Gait Disorders, Neurologic);基因表达调控, 发育期(Gene Expression Regulation, Developmental);神经胶质原纤维酸性蛋白质(Glial Fibrillary Acidic Protein);图像处理, 计算机辅助(Image Processing, Computer-Assisted);男(雄)性(Male);大鼠(Rats);受体, 红细胞生成素(Receptors, Erythropoietin);统计学, 非参数(Statistics, Nonparametric);协同转运子(Symporters);时间因素(Time Factors)
DOI
10.3171/2015.10.PEDS15554
PMID
26894518
发布时间
2023-12-13
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