Patient-derived ovarian cancer xenografts re-growing after a cisplatinum treatment are less responsive to a second drug re-challenge: a new experimental setting to study response to therapy.
第一作者:
Francesca,Ricci
第一单位:
Department of Oncology, Laboratory of Molecular Pharmacology, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
作者:
医学主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);癌, 子宫内膜样(Carcinoma, Endometrioid);细胞增殖(Cell Proliferation);顺铂(Cisplatin);抗药性, 肿瘤(Drug Resistance, Neoplasm);上皮-间质转化(Epithelial-Mesenchymal Transition);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);小鼠, 裸(Mice, Nude);肿瘤, 囊性, 黏液性和浆液性(Neoplasms, Cystic, Mucinous, and Serous);肿瘤干细胞(Neoplastic Stem Cells);卵巢肿瘤(Ovarian Neoplasms);时间因素(Time Factors);肿瘤负荷(Tumor Burden);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.18632/oncotarget.7465
PMID
26910918
发布时间
2022-04-09
- 浏览60
Oncotarget
7441-7451页
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