Novel Approach Targeting the Complex Pathophysiology of Hypertrophic Cardiomyopathy: The Impact of Late Sodium Current Inhibition on Exercise Capacity in Subjects with Symptomatic Hypertrophic Cardiomyopathy (LIBERTY-HCM) Trial.

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第一作者： Iacopo,Olivotto

第一单位： From the Referral Center for Cardiomyopathies, Careggi University Hospital, Florence, Italy (I.O.); Gilead Sciences, Inc, Foster City, CA (J.L.H., R.F.-F., C.B., L.B.); Department of Preclinical and Clinical Pharmacology and Center of Molecular Medicine, University of Florence, Florence, Italy (R.C.); Veterans Affairs Palo Alto Health Care System and Stanford University, Palo Alto, CA (J.M.); and Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, Boston, MA (M.S.M.). olivottoi@aou-careggi.toscana.it.

作者： Iacopo,Olivotto ^[1] ; Jennifer L,Hellawell ^[2] ; Ramin,Farzaneh-Far ^[2] ; Christiana,Blair ^[2] ; Raffaele,Coppini ^[2] ; Jonathan,Myers ^[2] ; Luiz,Belardinelli ^[2] ; Martin S,Maron ^[2]

作者单位： From the Referral Center for Cardiomyopathies, Careggi University Hospital, Florence, Italy (I.O.); Gilead Sciences, Inc, Foster City, CA (J.L.H., R.F.-F., C.B., L.B.); Department of Preclinical and Clinical Pharmacology and Center of Molecular Medicine, University of Florence, Florence, Italy (R.C.); Veterans Affairs Palo Alto Health Care System and Stanford University, Palo Alto, CA (J.M.); and Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, Boston, MA (M.S.M.). olivottoi@aou-careggi.toscana.it. ^[1] From the Referral Center for Cardiomyopathies, Careggi University Hospital, Florence, Italy (I.O.); Gilead Sciences, Inc, Foster City, CA (J.L.H., R.F.-F., C.B., L.B.); Department of Preclinical and Clinical Pharmacology and Center of Molecular Medicine, University of Florence, Florence, Italy (R.C.); Veterans Affairs Palo Alto Health Care System and Stanford University, Palo Alto, CA (J.M.); and Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, Boston, MA (M.S.M.). ^[2]

关键词 cardiomyopathy, hypertrophic clinical trial death, sudden, cardiac diagnostic imaging morbidity