Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models.

导出 OA

翻译打印收藏纠错

第一作者： Josephine Kam Tai,Dermawan

第一单位： Department of Cancer Biology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio. Department of Molecular Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio.

作者： Josephine Kam Tai,Dermawan ^[1] ; Masahiro,Hitomi ^[2] ; Daniel J,Silver ^[3] ; Qiulian,Wu ^[4] ; Poorva,Sandlesh ^[5] ; Andrew E,Sloan ^[6] ; Andrei A,Purmal ^[7] ; Katerina V,Gurova ^[5] ; Jeremy N,Rich ^[8] ; Justin D,Lathia ^[2] ; George R,Stark ^[9] ; Monica,Venere ^[10]

作者单位： Department of Cancer Biology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio. Department of Molecular Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio. ^[1] Department of Molecular Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio. Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio. ^[2] Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio. ^[3] Department of Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio. ^[4] Department of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, New York. ^[5] Brain Tumor and Neuro-Oncology Center and Department of Neurological Surgery, Case Western Reserve University School of Medicine, Cleveland, Ohio. ^[6] Cleveland BioLabs Inc., Buffalo, New York. ^[7] Department of Molecular Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio. Department of Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio. ^[8] Department of Cancer Biology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio. Department of Molecular Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio. starkg@ccf.org monica.venere@osumc.edu. ^[9] Department of Cancer Biology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio. Department of Molecular Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio. Department of Radiation Oncology, James Cancer Hospital and Comprehensive Cancer Center, The Ohio State University Wexner School of Medicine, Columbus, Ohio. starkg@ccf.org monica.venere@osumc.edu. ^[10]