The Need for Speed-Kinetic Limits of Drug Transporters.

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第一作者： Pär,Matsson

第一单位： Department of Pharmacy, Uppsala University, Box 580, 751 23 Uppsala, Sweden; Uppsala University Drug Optimization and Pharmaceutical Profiling Platform (UDOPP) - a node of the Chemical Biology Consortium Sweden, Uppsala, Sweden. Electronic address: par.matsson@farmaci.uu.se.

作者： Pär,Matsson ^[1] ; Patrik,Lundquist ^[2] ; Per,Artursson ^[3]

作者单位： Department of Pharmacy, Uppsala University, Box 580, 751 23 Uppsala, Sweden; Uppsala University Drug Optimization and Pharmaceutical Profiling Platform (UDOPP) - a node of the Chemical Biology Consortium Sweden, Uppsala, Sweden. Electronic address: par.matsson@farmaci.uu.se. ^[1] Department of Pharmacy, Uppsala University, Box 580, 751 23 Uppsala, Sweden. ^[2] Department of Pharmacy, Uppsala University, Box 580, 751 23 Uppsala, Sweden; Uppsala University Drug Optimization and Pharmaceutical Profiling Platform (UDOPP) - a node of the Chemical Biology Consortium Sweden, Uppsala, Sweden; Science for Life Laboratory Drug Discovery and Development Platform, Uppsala University, Uppsala, Sweden. Electronic address: per.artursson@farmaci.uu.se. ^[3]

关键词 carrier-mediated transport drug transport passive diffusion permeability systems biology transporter

主题词动物(Animals);细胞膜通透性(Cell Membrane Permeability);人类(Humans);膜转运蛋白质类(Membrane Transport Proteins)

DOI 10.1016/j.tips.2016.02.002

PMID 26922253

发布时间 2018-12-02

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准确一般字义偏差语意偏离译文作用小提交