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AZD8529, a positive allosteric modulator at the mGluR2 receptor, does not improve symptoms in schizophrenia: A proof of principle study.

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第一作者： Robert E,Litman

第一单位： CBH Health, LLC, 9210 Corporate Blvd., Suite 110, Rockville, MD, United States; Georgetown University, 3700 O St. NW, Washington, DC 20057, United States.

作者： Robert E,Litman ^[1] ; Mark A,Smith ^[2] ; James J,Doherty ^[3] ; Alan,Cross ^[4] ; Shane,Raines ^[5] ; Lev,Gertsik ^[6] ; Stephen R,Zukin ^[7]

作者单位： CBH Health, LLC, 9210 Corporate Blvd., Suite 110, Rockville, MD, United States; Georgetown University, 3700 O St. NW, Washington, DC 20057, United States. ^[1] AstraZeneca Pharmaceuticals, 1800 Concord Pike, Wilmington, DE 19542, United States; Teva Pharmaceuticals, 41 Moores Rd., Frazer, PA 19355, United States. ^[2] AstraZeneca Pharmaceuticals, 1800 Concord Pike, Wilmington, DE 19542, United States; Sage Therapeutics, 215 First St., Cambridge, MA 02142, United States. ^[3] AstraZeneca Pharmaceuticals, 1800 Concord Pike, Wilmington, DE 19542, United States. ^[4] AstraZeneca Pharmaceuticals, 1800 Concord Pike, Wilmington, DE 19542, United States; 2b Analytics, LLC, 128 Westminster Dr., Wallingford, PA 19086, United States. ^[5] California Clinical Trials Medical Group, 1560 East Chevy Chase Dr., Suite 140, Glendale, CA 91206, United States. ^[6] AstraZeneca Pharmaceuticals, 1800 Concord Pike, Wilmington, DE 19542, United States; Forest Research Institute, Jersey City, NJ, United States; Haborside Financial Center, Plaza V, Jersey City, NJ 07311, United States. ^[7]