17β-estradiol ameliorates age-associated loss of fibroblast function by attenuating IFN-γ/STAT1-dependent miR-7 upregulation.-论文-万方医学网

作者： Adam C,Midgley ^[1] ; Glyn,Morris ^[1] ; Aled O,Phillips ^[1] ; Robert,Steadman ^[1]

作者单位： Institute of Nephrology, Wales Kidney Research Unit, Division of Infection and Immunity, Cardiff University, College of Biomedical and Life Sciences, University Hospital of Wales, Heath Park, Wales, CF14 4XN, UK. ^[1]

主题词动物(Animals);碱基序列(Base Sequence);结合部位(Binding Sites);细胞分化(Cell Differentiation);细胞迁移分析(Cell Migration Assays);细胞增殖(Cell Proliferation);胶原(Collagen);雌二醇(Estradiol);成纤维细胞(Fibroblasts);凝胶类(Gels);炎症介导素类(Inflammation Mediators);干扰素γ(Interferon-gamma);微RNAs(MicroRNAs);启动区, 遗传(Promoter Regions, Genetic);蛋白质结合(Protein Binding);大鼠(Rats);受体, 雌激素(Receptors, Estrogen);STAT1转录因子(STAT1 Transcription Factor);转录, 遗传(Transcription, Genetic);转化生长因子β1(Transforming Growth Factor beta1);增量调节(Up-Regulation)

DOI 10.1111/acel.12462

PMID 26931423

发布时间 2018-11-13

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17β-estradiol ameliorates age-associated loss of fibroblast function by attenuating IFN-γ/STAT1-dependent miR-7 upregulation.

Aging cell

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17β-estradiol ameliorates age-associated loss of fibroblast function by attenuating IFN-γ/STAT1-dependent miR-7 upregulation.

Aging cell

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Aging cell

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