Multi-platform molecular profiling of a large cohort of glioblastomas reveals potential therapeutic strategies.

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作者： Joanne,Xiu ^[1] ; David,Piccioni ^[2] ; Tiffany,Juarez ^[2] ; Sandeep C,Pingle ^[2] ; Jethro,Hu ^[3] ; Jeremy,Rudnick ^[3] ; Karen,Fink ^[4] ; David B,Spetzler ^[1] ; Todd,Maney ^[1] ; Anatole,Ghazalpour ^[1] ; Ryan,Bender ^[1] ; Zoran,Gatalica ^[1] ; Sandeep,Reddy ^[1] ; Nader,Sanai ^[5] ; Ahmed,Idbaih ^[6] ; Michael,Glantz ^[7] ; Santosh,Kesari ^[8]

作者单位： Caris Life Sciences, Phoenix, AZ, USA. ^[1] Neuro-Oncology Program, Moores Cancer Center, UC San Diego, La Jolla, CA, USA. ^[2] Cedars-Sinai Medical Center, Los Angeles, CA, USA. ^[3] Baylor University Medical Center, Dallas, TX, USA. ^[4] Barrow Neurological Institute, Phoenix, AZ, USA. ^[5] AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service de Neurologie 2-Mazarin, Paris, France. ^[6] Sorbonne Universités, UPMC Univ Paris 06, UMRS 975, Institut du Cerveau et de la Moelle, Paris, France. ^[7] Inserm U 975, Paris, France. ^[8] CNRS, UMR 7225, Paris, France. ^[9] Pennsylvania State University, Hershey, PA, USA. ^[10] Translational Neuro-Oncology Laboratories, Department of Neurosciences UC San Diego, La Jolla, CA, USA. ^[11] Department of Translational Neuro-Oncology and Neurotherapeutics, John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA, USA. ^[12]

关键词 EGFRvIII IDH1 MGMT promoter methylation glioblastoma tumor profiling