Minimal hepatic glucose-6-phosphatase-α activity required to sustain survival and prevent hepatocellular adenoma formation in murine glycogen storage disease type Ia.
第一作者:
Young Mok,Lee
第一单位:
Section on Cellular Differentiation, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, United States.
作者:
关键词
AAV, adeno-associated virusBW, body weightER, endoplasmic reticulumG6P, glucose-6-phosphateG6PC, glucose-6-phosphatase-α geneG6PT, glucose-6-phosphate transporterG6Pase-α, glucose-6-phosphatase-αGPE, G6PC promoter and enhancerGSD-Ia, glycogen storage disease type IaGene therapyGlucose homeostasisGlucose-6-phosphate transporterHCA, hepatocellular adenomaRecombinant adeno-associated virus vector
DOI
10.1016/j.ymgmr.2015.03.001
PMID
26937391
发布时间
2020-09-29
- 浏览88
Molecular genetics and metabolism reports
2015年3卷
28-32页
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