Polymorphisms in α-Defensin-Encoding DEFA1A3 Associate with Urinary Tract Infection Risk in Children with Vesicoureteral Reflux.

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作者： Andrew L,Schwaderer ^[1] ; Huanyu,Wang ^[1] ; SungHwan,Kim ^[2] ; Jennifer M,Kline ^[3] ; Dong,Liang ^[4] ; Pat D,Brophy ^[5] ; Kirk M,McHugh ^[6] ; George C,Tseng ^[2] ; Vijay,Saxena ^[1] ; Evan,Barr-Beare ^[1] ; Keith R,Pierce ^[4] ; Nader,Shaikh ^[7] ; J Robert,Manak ^[8] ; Daniel M,Cohen ^[3] ; Brian,Becknell ^[1] ; John D,Spencer ^[1] ; Peter B,Baker ^[9] ; Chack-Yung,Yu ^[10] ; David S,Hains ^[11]

作者单位： The Centers for Clinical and Translational Medicine and. ^[1] Departments of Biostatistics and. ^[2] Emergency Medicine and. ^[3] Innate Immunity Translational Research Center, Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee. ^[4] Division of Nephrology, Department of Pediatrics, University of Iowa Children's Hospital, Iowa City, Iowa. ^[5] Division of Anatomy, The Ohio State University, Columbus, Ohio. ^[6] Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania. ^[7] Departments of Biology and Pediatrics, University of Iowa, Iowa; and. ^[8] Department of Pathology, Nationwide Children's Hospital, Columbus, Ohio. ^[9] Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio. ^[10] Innate Immunity Translational Research Center, Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee; Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee dhains@uthsc.edu. ^[11]

关键词 genetics and development pyelonephritis vesico-ureteral reflux