SUMOylation of KLF4 acts as a switch in transcriptional programs that control VSMC proliferation.

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作者： Chan-Juan,Nie ^[1] ; Yong Hui,Li ^[2] ; Xin-Hua,Zhang ^[1] ; Zhi-Peng,Wang ^[1] ; Wen,Jiang ^[1] ; Yu,Zhang ^[1] ; Wei-Na,Yin ^[1] ; Yong,Zhang ^[3] ; Hui-Jing,Shi ^[1] ; Yan,Liu ^[1] ; Cui-Ying,Zheng ^[1] ; Jing,Zhang ^[1] ; Guo-Liang,Zhang ^[4] ; Bin,Zheng ^[5] ; Jin-Kun,Wen ^[6]

作者单位： Department of Biochemistry and Molecular Biology, Hebei Medical University, Zhongshan East Road, Shijiazhuang 050017, China. ^[1] Department of Biochemistry and Molecular Biology, Hebei Medical University, Zhongshan East Road, Shijiazhuang 050017, China; Hebei Center for Disease Control and Prevention, Shijiazhuang 050000, China. ^[2] Department of Urinary Surgery, Second Hospital of Hebei Medical University, Pingan Road, Shijiazhuang 050000, China. ^[3] Third Hospital of Shijiazhuang, Shijiazhuang 050000, China. ^[4] Department of Biochemistry and Molecular Biology, Hebei Medical University, Zhongshan East Road, Shijiazhuang 050017, China. Electronic address: doublezb@hebmu.edu.cn. ^[5] Department of Biochemistry and Molecular Biology, Hebei Medical University, Zhongshan East Road, Shijiazhuang 050017, China. Electronic address: wjk@hebmu.edu.cn. ^[6]

关键词 KLF4 Proliferation SUMOylation Ubc9 VSMC