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首页> Toxicological sciences : an official journal of the Society of Toxicology> Vinyl Chloride Metabolites Potentiate Inflammatory Liver Injury Caused by LPS in Mice.

Vinyl Chloride Metabolites Potentiate Inflammatory Liver Injury Caused by LPS in Mice.

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作者： Lisanne C,Anders ^[1] ; Anna L,Lang ^[2] ; Anwar,Anwar-Mohamed ^[2] ; Amanda N,Douglas ^[2] ; Adrienne M,Bushau ^[2] ; Keith Cameron,Falkner ^[3] ; Bradford G,Hill ^[4] ; Nikole L,Warner ^[5] ; Gavin E,Arteel ^[2] ; Matt,Cave ^[6] ; Craig J,McClain ^[6] ; Juliane I,Beier ^[7]

作者单位： *Department of Pharmacology and Toxicology Department of Medicine. ^[1] *Department of Pharmacology and Toxicology. ^[2] Department of Medicine. ^[3] Department of Medicine Diabetes and Obesity Center. ^[4] Department of Microbiology and Immunology, University of Louisville Health Sciences Center, Louisville, Kentucky 40292; and. ^[5] *Department of Pharmacology and Toxicology Department of Medicine Robley Rex Louisville VAMC, Louisville, Kentucky 40206. ^[6] *Department of Pharmacology and Toxicology juliane.beier@louisville.edu. ^[7]

关键词 PVC TASH hepatotoxicity.toxicant-associated steatohepatitis vinyl chloride metabolite

主题词 AMP活化蛋白激酶类(AMP-Activated Protein Kinases);乙醛(Acetaldehyde);动物(Animals);碳水化合物代谢(Carbohydrate Metabolism);基因表达调控(Gene Expression Regulation);Hep G2细胞(Hep G2 Cells);人类(Humans);脂类代谢(Lipid Metabolism);脂多糖类(Lipopolysaccharides);肝(Liver);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);线粒体, 肝(Mitochondria, Liver);磷酰化(Phosphorylation);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);时间因素(Time Factors);氯乙烯(Vinyl Chloride)

DOI 10.1093/toxsci/kfw045

PMID 26962056

发布时间 2021-12-04

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Toxicological sciences : an official journal of the Society of Toxicology

Toxicological sciences

2016年151卷2期

312-23页

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