HDAC Inhibitors Enhance T-Cell Chemokine Expression and Augment Response to PD-1 Immunotherapy in Lung Adenocarcinoma.

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第一作者： Hong,Zheng

第一单位： Department of Immunology, Moffitt Cancer Center, Tampa, Florida.

作者： Hong,Zheng ^[1] ; Weipeng,Zhao ^[2] ; Cihui,Yan ^[2] ; Crystina C,Watson ^[3] ; Michael,Massengill ^[1] ; Mengyu,Xie ^[3] ; Chris,Massengill ^[1] ; David R,Noyes ^[1] ; Gary V,Martinez ^[4] ; Roha,Afzal ^[4] ; Zhihua,Chen ^[5] ; Xiubao,Ren ^[6] ; Scott J,Antonia ^[7] ; Eric B,Haura ^[8] ; Brian,Ruffell ^[9] ; Amer A,Beg ^[10]

作者单位： Department of Immunology, Moffitt Cancer Center, Tampa, Florida. ^[1] Department of Immunology, Moffitt Cancer Center, Tampa, Florida. Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China. ^[2] Department of Immunology, Moffitt Cancer Center, Tampa, Florida. Department of Cancer Biology PhD Program, University of South Florida, Tampa, Florida. ^[3] Department of Cancer Imaging and Metabolism, Moffitt Cancer Center, Tampa, Florida. ^[4] Department of Bioinformatics, Moffitt Cancer Center, Tampa, Florida. ^[5] Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China. ^[6] Department of Immunology, Moffitt Cancer Center, Tampa, Florida. Department of Thoracic Oncology, Moffitt Cancer Center, Tampa, Florida. ^[7] Department of Thoracic Oncology, Moffitt Cancer Center, Tampa, Florida. ^[8] Department of Immunology, Moffitt Cancer Center, Tampa, Florida. Department of Breast Oncology, Moffitt Cancer Center, Tampa, Florida. ^[9] Department of Immunology, Moffitt Cancer Center, Tampa, Florida. Department of Thoracic Oncology, Moffitt Cancer Center, Tampa, Florida. amer.beg@moffitt.org. ^[10]