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Genome-wide discovered psychosis-risk gene ZNF804A impacts on white matter microstructure in health, schizophrenia and bipolar disorder.

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第一作者： Emma-Jane,Mallas

第一单位： Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, University of London, London, United Kingdom; Computational, Cognitive and Clinical Neuroimaging Laboratory, Division of Brain Sciences, Department of Medicine, Imperial College London, London, United Kingdom.

作者： Emma-Jane,Mallas ^[1] ; Francesco,Carletti ^[2] ; Christopher A,Chaddock ^[3] ; James,Woolley ^[4] ; Marco M,Picchioni ^[5] ; Sukhwinder S,Shergill ^[3] ; Fergus,Kane ^[6] ; Matthew P G,Allin ^[3] ; Gareth J,Barker ^[7] ; Diana P,Prata ^[8]

作者单位： Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, University of London, London, United Kingdom; Computational, Cognitive and Clinical Neuroimaging Laboratory, Division of Brain Sciences, Department of Medicine, Imperial College London, London, United Kingdom. ^[1] Department of Neuroradiology, John Radcliffe Hospital, Oxford University Hospitals NHS Trust , Oxford , United Kingdom. ^[2] Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, University of London , London , United Kingdom. ^[3] Psychological Medicine, Royal Brompton & Harefield NHS Trust , London , United Kingdom. ^[4] Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, University of London, London, United Kingdom; St Andrew's Academic Department, St Andrew's Healthcare, Northampton, United Kingdom. ^[5] Department of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, University of London , London , United Kingdom. ^[6] Department of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, University of London , London , United Kingdom. ^[7] Department of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, University of London, London, United Kingdom; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal. ^[8]

关键词 Bipolar disorder Diffusion tensor imaging Fractional anisotropy Genome-wide association Psychosis Schizophrenia White matter ZNF804A

DOI 10.7717/peerj.1570

PMID 26966642

发布时间 2025-05-29

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Genome-wide discovered psychosis-risk gene ZNF804A impacts on white matter microstructure in health, schizophrenia and bipolar disorder.

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Genome-wide discovered psychosis-risk gene ZNF804A impacts on white matter microstructure in health, schizophrenia and bipolar disorder.

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